Download Advances in Cancer Research, Vol. 61 by George F. Vande Woude (ed.), George Klein (ed.) PDF

By George F. Vande Woude (ed.), George Klein (ed.)

Quantity sixty one of "Advances in melanoma study" comprises insurance of the next: molecular ways to melanoma remedy, radiation resistance, melanoma prevention study trials, mammalian gene amplification, retinoblastoma gene functionality, molecular genetic foundation of breast melanoma, and tumour merchandising by way of okadaic acid type compounds.

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1976). Cancer Res. 36, 2699. Sporn, M. B. (1991). Cancer Res. 51, 6215-6218. Steinmetz, K. , and Potter, J. D. (1991a). Cancer Causes Control 2, 325-357. Steinmetz, K. , and Potter, J. D. (1991b). Cancer Causes Control 2, 427-442. Stemmermann, G. , and Chyou, P. H. (1990). Dis. Colon Rectum 33, 190194. Taylor, J. A. (1989). A m . J . Epidemiol. 130, 6-13. Thun, M. , Namboodiri, M. , and Heath, C. , Jr. (1991). N . Engl. J . Med. 325, 15931596. S. Food and Drug Administration (1991). Fed. Regkter 56, 60566-60578.

R. (1984). J. Natl. Cancer Inst. 72, 13231325. Nigro, N. , Bull, A. , Klopfer, B. , el al. (1979). J. Natl. Cancer Inst. 62, 1097-1 102. Ratko, T. , Detrisac, C. J.. Dinger, N. , Thomas, C. , Kelloff, G. , and Moon, R. C. Cancer Res. 49,4472-4476. Reddy, B. S. Med. 16,559-565. Rose, D. P. Nutrition 8,47-51. Rose, D. , Connolly, J. , et al. Am. J . Clin. Nutr. 54, 520-525. , Palmer, J. , Zauber, A. G . ,Warshauer, M. , Stolley, P. , and Shapiro, S. J. Natl. Cancer Imt. 83, 355-358. ,and Ron, E. (1989).

Thus far, a tumor suppressor gene has been identified for only four regions of frequent allele loss: p53 on chromosome 17p; Rb on 13; DCC on 18; and prohibitin on 17q. In view of the high frequency of other allele losses, it is likely that many tumor suppressor genes remain to be discovered in breast cancer. 1 . , 1991). T h e region deleted includes the p53 gene. , 1989). , 1991). In the various tumor types studied, these point mutations are usually found in exons 5 , 6 , 7 , and 8 and result in amino acid substitutions of residues that are highly conserved during 42 MARC J.

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