By S. González-Moreno
This ebook stories present examine in peritoneal malignant dissemination, from its pathogenesis and molecular mechanisms to the most recent scientific trials. The publication covers the necessities of perioperative intraperitoneal chemotherapy and smooth histopathological overview of peritoneal floor malignancy. The book’s old point of view at the unfolding of recent wisdom issues the way in which for destiny learn. members comprise top specialists, between them the pioneers who gave delivery to this new period in oncology.
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Extra resources for Advances in Peritoneal Surface Oncology (Recent Results in Cancer Research, Volume 169)
Tatsumi K, Fukushima M, Shirasaka T et al. (1987) Inhibitory effect of pyrimidine, barbituric acid and pyrimidine derivatives on 5-fluorouracil degradation in rat liver extracts. Jpn J Cancer Res 78:748– 755 45. Van Groeningen CJ, Peters GJ, Schornagel JH et al. (2000) Phase I clinical and pharmacologic study 23 of oral S-1 in patients with advanced gastric solid tumor. J Clin Oncol 18:2772–2779 46. Hirata K, Horikoshi N, Aiba K et al. (1999) Pharmacokinetic study of S-1, a novel oral fluorouracil antitumor drug.
Br J Cancer 83:188–195 27. Yanagihara K, Takigahira M, Tanaka H et al. (2005) Development and biological analysis of peritoneal metastasis mouse models for human scirrhous stomach cancer. Cancer Sci 96:323–332 28. Sakakura, Takemura M, Hagiwara A C et al. (2004) Overexpression of dopa decarboxylase in peritoneal Y. Yonemura et al. dissemination of gastric cancer and its potential as a novel marker for the detection of peritoneal micrometastases with real-time RT-PCR. Br J Cancer 90:665– 671 29.
One could also argue that the commonplace advanced nature of gastric cancer at the time of resection, and the proximity of the serosal surface, may also be part of the explanation as to why serosal involvement is more likely to be seen on flat serosal surfaces in gastric cancer. Once again, the mechanisms underpinning this serosal involvement are very poorly understood and require much more basic research. 3 Pathological Evaluation and Implications of Serosal Involvement in Gastrointestinal Cancer 31 Fig.